Watching Game of Thrones will give a general sense of the world of Westeros; it’s medieval, it’s quite brutal and gritty and the politics can get rather ugly. However, the show does not give you a good sense of the culture and history of the Seven Kingdoms. Furthermore, visually it is often quite inaccurate, especially in terms of the clothing in King’s Landing.
Blood of Dragons MUSH is based solely on the book canon. Given this, players whose only experience of the setting is watching Game of Thrones are strongly encouraged to either read at least A Game of Thrones or research extensively, for example using the Concordance. The wiki can also be used but it does contain spoilers.
It is also important to note that the MUSH is set around 140 years before the start of the first book (and the start of the TV-show). The Targaryens are still in power and will remain so until Robert’s Rebellion